Diagnosis and Therapy of Localized Scleroderma
Identifieur interne : 001880 ( Main/Exploration ); précédent : 001879; suivant : 001881Diagnosis and Therapy of Localized Scleroderma
Auteurs : Alexander Kreuter [Allemagne] ; Thomas Krieg [Allemagne] ; Margitta Worm [Allemagne] ; Jörg Wenzel [Allemagne] ; Thilo Gambichler [Allemagne] ; Annegret Kuhn [Allemagne] ; Elisabeth Aberer [Allemagne] ; Karin Scharffetter-Kochanek [Allemagne] ; Nicolas Hunzelmann [Allemagne]Source :
- JDDG: Journal der Deutschen Dermatologischen Gesellschaft [ 1610-0379 ] ; 2009-09.
English descriptors
- Teeft :
- Acad, Acad dermatol, Active phase, Adult patients, Alexander kreuter, Annegret kuhn, Antinuclear antibodies, Arch dermatol, Arthritis rheum, Authors journal compilation blackwell verlag gmbh, Berlin jddg suppl, Borrelia burgdorferi, Corticosteroid, Deep type, Dermatol, Dermatology, Dermis, Differential diagnoses, Disease activity, Disease course, Early phase, Eosinophilic, Eosinophilic fasciitis, Expert commission, Fascia, Fasciitis, Fibroblast, Gambichler, Generalized type, Gmbh, Guideline, Hemiatrophy, Hunzelmann, Infiltrates, Inflammatory, Inflammatory infiltrates, Inflammatory reaction, Infrared thermography, Intralesional, Intralesional interferon, Jablonska, Jddg, Jddg supplement, Kerscher, Kreuter, Laboratory parameters, Laser doppler flowmetry, Lesion, Lilac ring, Limited type, Linear type, Linear types, Localized, Localized scleroderma, Methotrexate, Morphea, Neurological symptoms, Oral calcitriol, Original article, Pediatric, Pediatric patients, Phototherapy, Physical therapy, Plaque, Plaque type, Plasma cells, Present guideline, Puva, Rare variant, Rheumatoid factor, Rheumatol, Routine laboratory tests, Sabre, Scleroderma, Sclerosis, Sclerotic, Sclerotic lesions, Sclerotic skin disease, Steroid, Steroid therapy, Subtypes, Suppl, Systemic, Systemic scleroderma, Systemic sclerosis, Systemic steroids, Systemic therapy, Thermography, Thilo gambichler, Topical calcineurin inhibitors, Treatment concept, Treatment success, Ultrasound, Uva1, Uva1 phototherapy, Verlag, Weibel, Zulian.
Abstract
Localized scleroderma is a rare autoimmune disease with primary affection of the skin, and occasional involvement of the fat tissue, muscle, fascia, and bone. Depending on the clinical subtype, the spectrum of skin lesions ranges from singular plaque lesions to severe generalized or linear subtypes which may lead to movement restrictions and permanent disability. This German S1‐guideline proposes a classification of localized scleroderma that, considering the extent and depth of fibrosis, distinguishes limited, generalized, linear, and deep forms of localized scleroderma, together with its associated subtypes. The guideline includes a description of the pathogenesis, of differential diagnoses, and particular aspects of juvenile localized scleroderma, as well as recommendations for histopathologic, serologic, and biometric diagnostic procedures. Based on studies of topical and systemic treatments as well as phototherapy for localized scleroderma published in international literature, a treatment algorithm was developed which takes account of the different subtypes and the extent of disease.
Url:
DOI: 10.1111/j.1610-0387.2009.07178.x
Affiliations:
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Le document en format XML
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<term>Active phase</term>
<term>Adult patients</term>
<term>Alexander kreuter</term>
<term>Annegret kuhn</term>
<term>Antinuclear antibodies</term>
<term>Arch dermatol</term>
<term>Arthritis rheum</term>
<term>Authors journal compilation blackwell verlag gmbh</term>
<term>Berlin jddg suppl</term>
<term>Borrelia burgdorferi</term>
<term>Corticosteroid</term>
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<term>Dermatology</term>
<term>Dermis</term>
<term>Differential diagnoses</term>
<term>Disease activity</term>
<term>Disease course</term>
<term>Early phase</term>
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<term>Eosinophilic fasciitis</term>
<term>Expert commission</term>
<term>Fascia</term>
<term>Fasciitis</term>
<term>Fibroblast</term>
<term>Gambichler</term>
<term>Generalized type</term>
<term>Gmbh</term>
<term>Guideline</term>
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<term>Hunzelmann</term>
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<term>Infrared thermography</term>
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<term>Intralesional interferon</term>
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<term>Jddg supplement</term>
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<term>Kreuter</term>
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<term>Rheumatol</term>
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<term>Scleroderma</term>
<term>Sclerosis</term>
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<term>Sclerotic skin disease</term>
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<term>Thilo gambichler</term>
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<term>Treatment success</term>
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<front><div type="abstract" xml:lang="en">Localized scleroderma is a rare autoimmune disease with primary affection of the skin, and occasional involvement of the fat tissue, muscle, fascia, and bone. Depending on the clinical subtype, the spectrum of skin lesions ranges from singular plaque lesions to severe generalized or linear subtypes which may lead to movement restrictions and permanent disability. This German S1‐guideline proposes a classification of localized scleroderma that, considering the extent and depth of fibrosis, distinguishes limited, generalized, linear, and deep forms of localized scleroderma, together with its associated subtypes. The guideline includes a description of the pathogenesis, of differential diagnoses, and particular aspects of juvenile localized scleroderma, as well as recommendations for histopathologic, serologic, and biometric diagnostic procedures. Based on studies of topical and systemic treatments as well as phototherapy for localized scleroderma published in international literature, a treatment algorithm was developed which takes account of the different subtypes and the extent of disease.</div>
</front>
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<tree><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Kreuter, Alexander" sort="Kreuter, Alexander" uniqKey="Kreuter A" first="Alexander" last="Kreuter">Alexander Kreuter</name>
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<name sortKey="Aberer, Elisabeth" sort="Aberer, Elisabeth" uniqKey="Aberer E" first="Elisabeth" last="Aberer">Elisabeth Aberer</name>
<name sortKey="Gambichler, Thilo" sort="Gambichler, Thilo" uniqKey="Gambichler T" first="Thilo" last="Gambichler">Thilo Gambichler</name>
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<name sortKey="Kuhn, Annegret" sort="Kuhn, Annegret" uniqKey="Kuhn A" first="Annegret" last="Kuhn">Annegret Kuhn</name>
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